Potential new therapeutic intervention for ischemic stroke
نویسندگان
چکیده
منابع مشابه
Potential New Risk Factors for Ischemic Stroke
Background and Purpose—About 60% to 80% of all ischemic strokes can be attributed to increasing blood pressure, blood cholesterol, cigarette smoking, carotid stenosis, and diabetes mellitus (atherosclerotic ischemic stroke), and atrial fibrillation and valvular heart disease (cardiogenic ischemic stroke). The aim of this review was to examine the potential role of other risk factors in the etio...
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Acute ischemic stroke (AIS) is the leading cause of disability worldwide and among the leading causes of mortality. Although intravenous tissue plasminogen activator (IV-rtPA) was approved nearly 2 decades ago for treatment of AIS, only a minority of patients receive it due to a narrow time window for administration and several contraindications to its use. Endovascular approaches to recanaliza...
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Cannabis contains the psychoactive component delta⁸-tetrahydrocannabinol (delta⁸-THC), and the non-psychoactive components cannabidiol (CBD), cannabinol, and cannabigerol. It is well-known that delta⁸-THC and other cannabinoid CB₁ receptor agonists are neuroprotective during global and focal ischemic injury. Additionally, delta⁸-THC also mediates psychological effects through the activation of ...
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............................................................................................................................iii Acknowledgements...........................................................................................................v List of Figures...................................................................................................................ix
متن کاملProteolytic Extracellular Matrix Fragments Following Ischemic Stroke: New Insights to Potential Therapeutic Targets
Stroke is the leading cause of long-term disability and the third leading cause of death in the United States. The sudden disruption of blood flow that occurs following ischemic stroke ultimately leads to neuronal death, breakdown of the blood brain barrier, and proteolytic processing of the surrounding extracellular matrix (ECM). Within 3 days after ischemic stroke, new blood vessels begin to ...
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ژورنال
عنوان ژورنال: Journal of Translational Internal Medicine
سال: 2021
ISSN: 2224-4018
DOI: 10.2478/jtim-2021-0014